Quarterly report pursuant to Section 13 or 15(d)

STOCKHOLDERS' DEFICIT (Details Narrative)

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STOCKHOLDERS' DEFICIT (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 6 Months Ended
Feb. 26, 2021
Jun. 15, 2020
Dec. 29, 2017
Jun. 30, 2022
Jun. 30, 2022
Jun. 30, 2021
Mar. 31, 2021
Jun. 30, 2022
Jun. 30, 2021
Jun. 15, 2022
Dec. 31, 2021
Sep. 29, 2021
Feb. 09, 2021
Dec. 31, 2020
Class Of Warrant Or Right [Line Items]                            
Convertible notes principal amount       $ 23,326,000 $ 23,326,000     $ 23,326,000     $ 18,007,000      
Weighted average remaining ontractual life (years), outstanding               2 years 1 month 6 days            
Common stock, issued       49,558,501 49,558,501     49,558,501     49,311,864      
Share-based compensation               $ 10,000 $ 455,000          
Research and development         $ 298,000 $ 753,000   764,000 2,562,000          
Adjustment of warrants change in fair value increase additional paid in capital and accumulated loss               $ 446,000            
Common stock issued for services         $ 110,000   $ 500,000              
Common Stock [Member]                            
Class Of Warrant Or Right [Line Items]                            
Common stock issued for services (in shares)         246,637   324,675              
Common stock issued for services         $ 1,000                  
Amended and Restated Warrants [Member]                            
Class Of Warrant Or Right [Line Items]                            
Debt instrument exercise price       $ 0.446 $ 0.446     $ 0.446            
Number of common stock to be purchased               4,038,200            
Kainos Medicine, Inc [Member]                            
Class Of Warrant Or Right [Line Items]                            
Payments to research and development expense $ 500,000                          
Common stock shares issued for consideration 324,675                          
Addition to equity for common stock $ 500,000                          
Research and development               $ 0 1,000,000.0          
Stock Options [Member]                            
Class Of Warrant Or Right [Line Items]                            
Vesting period remaining for recognition of unrecognized share-based compensation expense               1 year            
Restricted Stock [Member] | Professional Relations and Consulting Service [Member] | Common Stock [Member]                            
Class Of Warrant Or Right [Line Items]                            
Common stock issued for services (in shares)       246,637                    
Common stock issued for services       $ 110,000                    
2021 Stock Incentive Option Plan [Member]                            
Class Of Warrant Or Right [Line Items]                            
Common stock, issued                       4,000,000    
Unrecognized share-based compensation expense       $ 11,000 $ 11,000     $ 11,000            
2021 Stock Incentive Option Plan [Member] | Stock Options [Member]                            
Class Of Warrant Or Right [Line Items]                            
Share-based compensation         $ 5,000 $ 274,000   $ 10,000 $ 450,000          
Convertible Promissory Note [Member]                            
Class Of Warrant Or Right [Line Items]                            
Number outstanding                   1,250,000 1,250,000      
Convertible Promissory Note [Member] | Securities Purchase Agreement [Member]                            
Class Of Warrant Or Right [Line Items]                            
Convertible notes principal amount   $ 3,150,000                        
Debt instrument exercise price   $ 2.05                        
Extended maturity date   Jun. 15, 2023                        
Percentage of monthly payments interest rate   12.00%                     2.00% 11.00%
Expected life (in years)   5 years                        
Number outstanding   1,250,000                        
Outstanding shares repayment   500,000                        
Repayment of debt   $ 0                        
GPB Debt Holdings II, LLC [Member] | Senior Secured Convertible Promissory Note [Member]                            
Class Of Warrant Or Right [Line Items]                            
Debt face amount percentage     240,764                      
Debt instrument exercise price     $ 10.80                      
Initial warrants exercisable period after issuance     5 years                      
GPB Debt Holdings II, LLC [Member] | Convertible Debt [Member] | Senior Secured Convertible Promissory Note [Member]                            
Class Of Warrant Or Right [Line Items]                            
Convertible notes principal amount     $ 13,000,000                      
Convertible notes aggregate purchase price     $ 12,500,000                      
Original issue discount percentage     4.00%                      
Debt instrument, repaid date     2018-02