Quarterly report pursuant to Section 13 or 15(d)

STOCKHOLDERS' DEFICIT (Details Narrative)

v3.21.2
STOCKHOLDERS' DEFICIT (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 26, 2021
Jun. 15, 2020
Feb. 28, 2020
Feb. 21, 2020
Dec. 29, 2017
Oct. 31, 2018
Mar. 31, 2021
Mar. 31, 2020
Dec. 31, 2020
Mar. 08, 2021
Feb. 09, 2021
Feb. 29, 2020
Jan. 31, 2020
Jul. 17, 2019
Jul. 16, 2019
Dec. 31, 2018
Class Of Warrant Or Right [Line Items]                                
Convertible notes principal amount             $ 16,911,000   $ 13,574,000              
Debt instrument exercise price       $ 3.00                 $ 5.87      
Percentage of monthly payments interest rate       10.00%                        
Maturity date       Apr. 21, 2021                        
Conversion debentures price       $ 3.00                 $ 9.52      
Share-based compensation expense             $ 181,000 $ 209,000                
Vesting period remaining for recognition of unrecognized compensation expense             7 months 6 days                  
Addition to equity for common stock               $ 142,000                
Kainos Medicine, Inc [Member]                                
Class Of Warrant Or Right [Line Items]                                
Common stock shares issued for consideration 324,675                              
Addition to equity for common stock $ 500,000                              
Payments to research and development expense $ 500,000                              
Common Stock [Member]                                
Class Of Warrant Or Right [Line Items]                                
Common stock shares issued for consideration               515,743                
Addition to equity for common stock               $ 1,000                
2011 Stock Incentive Option Plan [Member]                                
Class Of Warrant Or Right [Line Items]                                
Total unrecognized compensation expense             $ 294,000                  
2011 Stock Incentive Option Plan [Member] | Adjustment of Merger Exchange Ratio [Member]                                
Class Of Warrant Or Right [Line Items]                                
Exercisable term             10 years                  
2011 Stock Incentive Option Plan [Member] | Adjustment of Merger Exchange Ratio [Member] | Common Stock [Member]                                
Class Of Warrant Or Right [Line Items]                                
Stock options granted to purchase common stock             0   90,000              
2011 Stock Incentive Option Plan [Member] | Adjustment of Merger Exchange Ratio [Member] | Share Based Compensation Award, Tranche One [Member]                                
Class Of Warrant Or Right [Line Items]                                
Vesting period             1 year                  
Vesting percentage             33.33%                  
2011 Stock Incentive Option Plan [Member] | Adjustment of Merger Exchange Ratio [Member] | Share Based Compensation Award, Tranche Two [Member]                                
Class Of Warrant Or Right [Line Items]                                
Vesting period             2 years                  
Vesting percentage             66.67%                  
2011 Stock Incentive Option Plan [Member] | Stock Options [Member]                                
Class Of Warrant Or Right [Line Items]                                
Number of shares authorized under the plan                               9,000,000
Expiration period             10 years                  
Vesting period             3 years                  
Share-based compensation expense             $ 200,000 $ 200,000                
Amended and Restated Warrants [Member]                                
Class Of Warrant Or Right [Line Items]                                
Debt instrument exercise price             $ 1.54         $ 2.00   $ 5.87    
Amended and Restated Debentures [Member]                                
Class Of Warrant Or Right [Line Items]                                
Debt instrument exercise price       2.00                        
Conversion debentures price       $ 2.00                        
Initial shares under purchase agreement       100,000                        
Stock price       $ 2.00                        
10% Secured Senior Debentures [Member]                                
Class Of Warrant Or Right [Line Items]                                
Percentage of monthly payments interest rate                   10.00%            
Convertible Promissory Note [Member]                                
Class Of Warrant Or Right [Line Items]                                
Stock price             $ 1.71   $ 1.68              
Number outstanding             1,250,000   1,250,000              
Convertible Promissory Note [Member] | Securities Purchase Agreement [Member]                                
Class Of Warrant Or Right [Line Items]                                
Convertible notes principal amount   $ 3,150,000                            
Debt instrument exercise price   $ 2.05                            
Percentage of monthly payments interest rate   12.00%             11.00%   2.00%          
Conversion price                     $ 1.48          
Extended maturity date   Jun. 15, 2023                            
Expected life (in years)   5 years                            
Number outstanding   1,250,000                            
Convertible Promissory Note [Member] | Maximum [Member] | Securities Purchase Agreement [Member]                                
Class Of Warrant Or Right [Line Items]                                
Convertible notes aggregate purchase price                     $ 17,000,000          
GPB Debt Holdings II, LLC [Member] | Amended and Restated Warrants [Member]                                
Class Of Warrant Or Right [Line Items]                                
Debt instrument exercise price                             $ 10.00  
GPB Debt Holdings II, LLC [Member] | Maximum [Member] | Amended and Restated Warrants [Member]                                
Class Of Warrant Or Right [Line Items]                                
Debt face amount percentage                             1,460,000  
GPB Debt Holdings II, LLC [Member] | Senior Secured Convertible Promissory Note [Member]                                
Class Of Warrant Or Right [Line Items]                                
Debt face amount percentage         240,764                      
Debt instrument exercise price         $ 10.80                      
Initial warrants exercisable period after issuance         5 years                      
GPB Debt Holdings II, LLC [Member] | Purchase Agreement With 10% Senior Secured Debentures [Member] | Securities Purchase Agreement [Member]                                
Class Of Warrant Or Right [Line Items]                                
Percentage of monthly payments interest rate           10.00%                    
Principal amount of debentures and warrants issued           $ 12,200,000                    
Debenture and warrants issued to original loan           $ 13,200,000                    
GPB Debt Holdings II, LLC [Member] | Purchase Agreement With 10% Senior Secured Debentures [Member] | Maximum [Member] | Securities Purchase Agreement [Member]                                
Class Of Warrant Or Right [Line Items]                                
Number of common stock to be purchased           1,220,000                    
GPB Debt Holdings II, LLC [Member] | Amended and Restated Debentures [Member]                                
Class Of Warrant Or Right [Line Items]                                
Conversion price                             $ 10.00  
GPB Debt Holdings II, LLC [Member] | Convertible Debt [Member] | Senior Secured Convertible Promissory Note [Member]                                
Class Of Warrant Or Right [Line Items]                                
Convertible notes principal amount         $ 13,000,000                      
Convertible notes aggregate purchase price         $ 12,500,000                      
Original issue discount percentage         4.00%                      
Lincoln Park Capital Fund, LLC [Member]                                
Class Of Warrant Or Right [Line Items]                                
Initial shares under purchase agreement     100,000                          
Stock price     $ 2.00                          
Maximum number of common shares elect to sell     25,000,000                          
Maximum purchase shares of common stock     20,000                          
Maximum purchase of common stock in single regular purchase     $ 1,000,000                          
Termination cost or penalty     $ 0                          
Common stock shares issued for consideration     415,743                          
Addition to equity for common stock     $ 750,000                          
Lincoln Park Capital Fund, LLC [Member] | Minimum [Member] | Common Stock [Member]                                
Class Of Warrant Or Right [Line Items]                                
Equity method investment, ownership percentage     4.99%