EXHIBIT 32.1 CERTIFICATION PURSUANT TO 18 U.S.C. SECTION 1350 AS ADOPTED PURSUANT TO SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002 Pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002, in connection with the filing of the Quarterly Report on Form 10-QSB for the Quarter Ended June 30, 2008 (the "Report") by CNS Response, Inc. ("Registrant"), each of the undersigned hereby certifies that: 1. to the best of our knowledge, the Report fully complies with the requirements of section 13(a) or 15(d) of the Securities Exchange Act of 1934; and 2. to the best of our knowledge, the information contained in the Report fairly presents, in all material respects, the financial condition and results of operations of Registrant. Date: August 14, 2008 /s/ Leonard J. Brandt --------------------------- Leonard J. Brandt Chief Executive Officer Date: August 14, 2008 /s/ Horace Hertz --------------------------- Horace Hertz Chief Financial Officer